Lifelines provides many opportunities for good research

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Lifelines provides many opportunities for good research

Download our extensive data overview to get an insight in the population based Lifelines cohort study and biobank. It provides a unique overview of available data and biomaterials, and explains how to get access to the materials.

Lifelines provides many opportunities for good research

  • Data collection of 167,000 participants

  • Including 3 generations

  • Followed for 30 years

  • Diverse expert fields

  • Recalling of participants

Why Lifelines?

Lifelines is a large, multi-generational, prospective cohort study that includes over 167,000 participants (10%) from the northern population of the Netherlands. Through the length, size and in-depth examination we provide many excellent opportunities for studies worldwide unraveling the etiology of multifactorial diseases focusing on multifactor risk factors.

Customized collection possibilities

Lifelines has an open protocol, which means that you may request the collection of extra data, measurements and/or samples from Lifelines participants to suit your specific research needs. A unique feature is the possibility for researchers to collect additional data or biomaterials by recalling participants and to analyse these in combination with general Lifelines data and samples. 

Experiences of other researchers

At the moment more than 300 publications have been published for which Lifelines-data has been used. These researchers share their experience working with Lifelines and how it benefited their work.

“For the ImaLife project we investigate early imaging biomarkers of cardiovascular disease, lung cancer and chronic obstructive lung diseases. In total, 12,000 Lifelines participants undergo low-dose CT imaging of heart and lungs.”

Prof. dr. Rozemarijn Vliegenthart Radiologist

"Among Lifelines participants, we found that 10% used systemic or local corticosteroids, which implicates that these potential side effects may have important negative effects on public health.”

Prof. dr. Elisabeth van Rossum Professor in the field of obesity and biological stress

"Lifelines offers a broad biobank with many options for research. The possibility to obtain more data of our interest in a timely fashion was also essential for our project. It is great that this data will be available for further studies."

Linda van Kerkhof Researcher RIVM

Study design

The Lifelines study follows over 167,000 participants over a 30-year period. Every five years, participants visit one of the Lifelines sites in the northern parts of the Netherlands for an examination. During these assessments, several physical measurements are taken and different biomaterials are collected. As part of the assessment, participants are asked to fill out comprehensive questionnaires. In between assessments, participants are invited to complete follow-up questionnaires approximately once every 1.5 years.

What is your next step?

In our extensive data overview you can find detailed information about our collection of data and samples. You can download this by filing in the form at the top of this page. Do you have any questions about the next step in your research? Feel free to contact us, we are happy to help you. 

Institutes that we work with

logo Amsterdam UMC
logo centraal bureau
logo centre universitaire
logo paiga
logo university of cambridge
logo wageningen university
logo UMCG
logo groningen university