Publication: Anxiety disorders and CRP in a population cohort study with 54326 participants - The Lifelines study


Researchers: Naudé PJW, Roest AM, Stein DJ, de Jonge P, Doornbos B.


Growing evidence indicates that inflammatory processes may play a role in the pathogenesis of anxiety disorders. Nevertheless, much remains to be learned about the involvement of inflammation, including C-reactive protein (CRP), in specific anxiety disorders. This study examines the relation between anxiety disorders and CRP.


Panic disorder with agoraphobia is associated with increased CRP, although the effect size of this association is small. This indicates that neuroinflammatory mechanisms may play a potential role in its pathophysiology.