Publication: Blood eosinophil count and metabolic, cardiac and pulmonary outcomes: A Mendelian randomization study

01-05-2018

Researchers: Amini M, Vonk JM, Abbasi A, Prins BP, Alizadeh BZ, et al.

Aim

Blood eosinophil count is associated with a variety of common complex outcomes in epidemiological observation. The aim of this study was to explore the causal association between determined blood eosinophil count and 20 common complex outcomes (10 metabolic, 6 cardiac, and 4 pulmonary).

Conclusion

An elevated eosinophil count is unlikely to be causally associated to higher risk of metabolic, cardiac, and pulmonary outcomes. Further studies with a stronger genetic risk score for eosinophil count may support these results.